Define gut: guts : the internal organs of an animal — gut in a sentence. guts definition: Noun 1. plural form of gut 2. The entrails or contents of the abdomen. 3. (slang) Courage; determination. 4. (slang) Content, substance. Is the main character of the anime/manga series Berserk. Guts is a mercenary with incredible strength and will while not superhuman his physical attributes are. What does the Australian term cobber mean? Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Logged-in users can add themselves to the map. Delivered to your inbox! ANCUD, Chile—On a recent day in this remote island town, Dr.